Fig 3. Ceramide profile in maternal plasma of PE and CTL patients.
Each target analyte: (ceramide (Cer) species) was analyzed by reversed-phase HPLC-MS/MS and identified by its specific parent-daughter ion mass transition and retention time. Different ceramide species: Cer 14:0 (A), Cer 14:0 in 1st trimester plasma of PE and CTL patients (B), Cer 16:0 (C), Cer 18:0 (D), Cer 24:0 (E) and SM 24:1 (F) were measured in plasma of 7 normotensive control (CTL) and 7 preeclamptic (PE) patients across gestation: first-, second- and third trimester. Data expressed as means ± SD. Statistical differences detected between groups are indicated with an asterisk (n = 7 for each group, p<0.05).