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. 2017 Mar 29;12:2489–2504. doi: 10.2147/IJN.S123190

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© 2017 Zhao et al. This work is published and licensed by Dove Medical Press Limited

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Cell viability and induction of apoptosis in MCF-7 cells.

Notes: (A) MTT assay of C₁₆-SS-CS-mPEG micelles and C₁₆-CC-CS-mPEG micelles in HEK293 cells after incubation for 24 h. (B) Cytotoxicity effects on MCF-7 cells of different micelles with, or without, drugs being loaded after incubation for 24 h. Measurement of cell apoptosis by (C) annexin V/PI double staining and (D) TUNEL assay and DAPI staining.

Abbreviations: C₁₆-SS-CS-mPEG, monomethoxy-poly(ethylene glycol)-chitosan-S-S-hexadecyl; C₁₆-CC-CS-mPEG, monomethoxy-poly(ethylene glycol)-chitosan-C-C-hexadecyl; Cur, curcumin; PBS, phosphate-buffered saline.