Table 3. Results of Meropenem Hydrolysis Assay (MHA) in case of intact or degraded drug in 58 Enterobacteriaceae strains included in the panel III.

Carbapenem susceptibility	Carbapenemase type/resistance mechanism	Microorganism	No. of strains	MHA
				Intact drug (n = 22)		Degraded drug (n = 36)
				CNP	CP	CNP	CP	CAV
Carbapenem nonsusceptible			21	13	8	0	0	NA
	NDM (1)	E.coli	1		1
	OXA-48 (1)	K.pneumoniae	1		1
	Class B^ (6)	K. pneumoniae	5		5
		E. coli	1		1
	Unknown ^^(13)	E.cloacae	5	5
		K. pneumoniae	4	4
		E.coli	3	3
		E. aerogenes	1	1
Carbapenem susceptible			37	1	0	36	0	-0.19/0.23
	AmpC (1)	E. cloacae	1			1		-0.06
	ESBL (36)	E. coli	21	1		20		-0.15/0.15
		K. pneumoniae	10			10		-0.15/0.19
		P. mirabilis	3			3		-0.15/0.23
		C. freundii	2			2		-0.19/-0.05
Total			58	14	8	36	0

CNP: carbapenemase nonproducer;

CP: carbapenemase producer;

CAV: carbapenemase activity value;

NA: not applicable;

^ Class B carbapenemase strains other than NDM and VIM;

^^ Carbapenemase-nonproducing enterobacteriaceae resistant to carbapenems.