Table 2.
Rome IV Classification of the Functional Gastrointestinal Disorders–Disorders of Gut-Brain Interaction
| A. Esophageal disorders | |
|---|---|
| A1. Functional chest pain | A4. Globus |
| A2. Functional heartburn | A5. Functional dysphagia |
| A3. Reflux hypersensitivity | |
|
| |
| B. Gastroduodenal disorders | |
|
| |
| B1. Functional dyspepsia | B3. Nausea and vomiting disorders |
| B1a. Postprandial distress syndrome | B3a. Chronic nausea vomiting syndrome |
| B1b. Epigastric pain syndrome | B3b. Cyclic vomiting syndrome |
| B2. Belching disorders | B3c. Cannabinoid hyperemesis syndrome |
| B2a. Excessive supragastric belching | B4. Rumination syndrome |
| B2b. Excessive gastric belching | |
|
| |
| C. Bowel disorders | |
|
| |
| C1. Irritable bowel syndrome | C2. Functional constipation |
| IBS with predominant constipation | C3. Functional diarrhea |
| IBS with predominant diarrhea | C4. Functional abdominal bloating/distension |
| IBS with mixed bowel habits | C5. Unspecified functional bowel disorder |
| IBS unclassified | C6. Opioid-induced constipation |
|
| |
| D. Centrally mediated disorders of gastrointestinal pain | |
|
| |
| D1. Centrally mediated abdominal pain syndrome | D2. Narcotic bowel syndrome/opioid-induced gastrointestinal hyperalgesia |
|
| |
| E. Gallbladder and sphincter of Oddi disorders | |
|
| |
| E1. Biliary pain | E2. Functional pancreatic sphincter of Oddi disorder |
| E1a. Functional gallbladder disorder | |
| E1b. Functional biliary Sphincter of Oddi disorder | |
|
| |
| F. Anorectal disorders | |
|
| |
| F1. Fecal incontinence | F3. Functional defecation disorders |
| F2. Functional anorectal pain | F3a. Inadequate defecatory propulsion |
| F2a. Levator ani syndrome | F3b. Dyssynergic defecation |
| F2b. Unspecified functional anorectal pain | |
| F2c. Proctalgia fugax | |
|
| |
| G. Childhood functional gastrointestinal disorders: neonate/toddler | |
|
| |
| G1. Infant regurgitation | G5. Functional diarrhea |
| G2. Rumination syndrome | G6. Infant dyschezia |
| G3. Cyclic vomiting syndrome | G7. Functional constipation |
| G4. Infant colic | |
|
| |
| H. Childhood functional gastrointestinal disorders: child/adolescent | |
|
| |
| H1. Functional nausea and vomiting disorders | H2. Functional abdominal pain disorders |
| H1a. Cyclic vomiting syndrome | H2a. Functional dyspepsia |
| H1b. Functional nausea and functional vomiting | H2a1. Postprandial distress syndrome |
| H1b1. Functional nausea | H2a2. Epigastric pain syndrome |
| H1b2. Functional vomiting disorders | H2b. Irritable bowel syndrome |
| H1c. Rumination syndrome | H2c. Abdominal migraine |
| H1d. Aerophagia | H2d. Functional abdominal pain - not otherwise specified |
| H3. Functional defecation | |
| H3a. Functional constipation | |
| H3b. Non-retentive fecal incontinence | |