Table 1. Characteristics of the population grouped according to the metabolic condition.
| Groups | Statistical comparison | Test post-hoc | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MHNO | MHO | MSO | MHNO vs MHO | MHO vs MSO | MHNO vs MSO | ||||||||
| M ± SD | M ± SD | M ± SD | P | MD | 95% CI MD | p | MD | 95% CI MD | p | MD | 95% CI MD | p | |
| n | 196 | 42 | 102 | ||||||||||
| Age (years) | 42 ± 15 | 44 ± 15 | 51 ± 14 | < 0.001 | -1.94 | -7.91/4.02 | NS | -7.04 | -13.47/-0.6 | 0.027 | -8.98 | -13.26/-4.69 | < 0.001 |
| BMI (kg m-2) | 24.52 ± 2.95 | 35.33 ± 6.65 | 36.94 ± 6.17 | < 0.001 | -10.82 | -12.73/-8.91 | < 0.001 | -1.61 | -3.67/0.45 | NS | -12.43 | -13.80/-11.06 | < 0.001 |
| WC (cm) | 86 ± 9 | 106 ± 10 | 112 ± 11 | < 0.001 | -19.53 | -23.61/-15.45 | < 0.001 | -5.97 | -10.37/-1.56 | 0.004 | -25.49 | -28.43/-22.56 | < 0.001 |
| FPG (mg dl-1) | 89 ± 10 | 90 ± 8 | 115 ± 49 | < 0.001 | -1.37 | -12.86/10.12 | NS | -24.55 | -36.94/-12.16 | < 0.001 | -25.92 | -34.17/-17.67 | < 0.001 |
| FSI (mcU ml-1) | 9.95 ± 7.44 | 12.91 ± 7.99 | 19.01 ± 15.99 | < 0.001 | -2.96 | -7.39/1.47 | NS | -6.10 | -10.87/-1.33 | 0.007 | -9.06 | -12.24/-5.88 | < 0.001 |
| HOMA | 2.23 ± 1.79 | 2.88 ± 1.79 | 5.53 ± 6.2 | < 0.001 | -0.65 | -2.17/0.87 | NS | -2.65 | -4.29/-1.01 | < 0.001 | -3.31 | -4.40/-2.21 | < 0.001 |
| HDL-C (mg dl-1) | 57 ± 13 | 55 ± 12 | 47 ± 12 | < 0.001 | 2.37 | -2.95/7.69 | NS | 7.97 | 2.23/13.71 | 0.003 | 10.34 | 6.52/14.16 | < 0.001 |
| TG (mg dl-1) | 97 ± 42 | 92 ± 36 | 166 ± 97 | < 0.001 | 4.59 | -21.44/30.62 | NS | -73.99 | -102.05/-45.93 | < 0.001 | -69.40 | -88.09/-50.71 | < 0.001 |
| SBP (mmHg) | 111 ± 19 | 121 ± 20 | 137 ± 21 | < 0.001 | -9.64 | -17.64/-1.65 | 0.012 | -15.45 | -24.07/-6.83 | < 0.001 | -25.09 | -30.83/-19.35 | < 0.001 |
| DBP (mmHg) | 69 ± 12 | 75 ± 14 | 83 ± 11 | < 0.001 | -6.11 | -10.92/-1.29 | 0.007 | -8.13 | -13.31/-2.94 | 0.001 | -14.23 | -17.69/-10.77 | < 0.001 |
| hs-CRP (mg l-1) | 2.01 ± 2.14 | 3.18 ± 2.60 | 3.89 ± 2.57 | < 0.001 | -1.17 | -2.23/-0.12 | 0.024 | -0.70 | -1.85/0.44 | NS | -1.88 | -2.62/-1.14 | < 0.001 |
Statistical evaluation: One way-ANOVA and Bonferroni post-hoc test.
MHNO: Metabolically Healthy Non-obese individuals; MHO: Metabolically Healthy Obese individuals; MSO: Obese individual with Metabolic Syndrome; M: mean; SD: standard deviation; MD: means difference; 95% CI MD: 95% confidence interval of the means difference; BMI: Body mass index; WC: Waist circumference; FPG: fasting plasma glucose; FSI: Fasting serum insulin; HOMA: Homoeostasis Model Assessment; HDL-C: high-density lipoprotein cholesterol; TG: triglycerides; SBP: systolic blood pressure; DBP: diastolic blood pressure; hs-CRP: High-Sensitive C reactive protein; NS: not significant.