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. 2017 Apr 6;12(4):e0174945. doi: 10.1371/journal.pone.0174945

Table 2. Characteristics of the population grouped according to the Metabolic Syndrome number of components.

A MetS number of components Statistical comparison
0 1 2 MetS
M ± SD M ± SD M ± SD M ± SD P
n 74 80 84 162
Age (years) 35 ± 10 39 ± 15 51 ± 14 53 ± 14 < 0.001
BMI (kg m-2) 24.23 ± 3.06 26.31 ± 5.34 28.48 ± 6.86 33.12 ± 7.14 < 0.001
WC (cm) 84 ± 10 89 ± 11 95 ± 13 105 ± 14 < 0.001
FPG (mg dl-1) 86 ± 8 89 ± 8 92 ± 11 112 ± 44 < 0.001
FSI (mcU ml-1) 10.14 ± 7.93 9.11 ± 5.88 12.07 ± 8.54 16.38 ± 13.96 < 0.001
HOMA 2.18 ± 1.81 2.02 ± 1.34 2.80 ± 2.08 4.68 ± 5.25 < 0.001
HDL-C (mg dl-1) 64 ± 11 52 ± 12 54 ± 14 47 ± 13 < 0.001
TG (mg dl-1) 78 ± 28 89 ± 31 117 ± 50 170 ± 97 < 0.001
SBP (mmHg) 103 ± 12 113 ± 20 122 ± 19 135 ± 21 < 0.001
DBP (mmHg) 65 ± 8 70 ± 12 76 ± 13 81 ± 12 < 0.001
hs-CRP (mg l-1) 1.70 ± 1.69 2.43 ± 2.49 2.43 ± 2.44 3.73 ± 2.48 < 0.001
B Test post-hoc
0 vs 1 0 vs 2 1 vs 2
MD 95% CI MD p MD 95% CI MD p MD 95% CI MD p
Age (years) -4.02 -9.84/1.81 NS -15.43 -21.19/-9.67 < 0.001 -11.42 -17.06/-5.77 < 0.001
BMI (kg m-2) -2.08 -4.72/0.55 NS -4.25 -6.85/-1.64 < 0.001 -2.17 -4.72/0.38 NS
WC (cm) -4.35 -9.57/0.87 NS -10.68 -15.84/-5.52 < 0.001 -6.33 -11.39/-1.28 0.006
FPG (mg dl-1) -3.43 -15.69/8.83 NS -6.42 -18.53/5.7 NS -2.98 -14.86/8.89 NS
FSI (mcU ml-1) 1.03 -3.56/5.61 NS -1.94 -6.47/2.6 NS -2.96 -7.37/1.45 NS
HOMA 0.16 -1.4/1.71 NS -0.62 -2.16/0.92 NS -0.78 -2.27/0.72 NS
HDL-C (mg dl-1) 11.50 6.16/16.84 < 0.001 9.46 4.18/14.74 < 0.001 -2.04 -7.2/3.11 NS
TG (mg dl-1) -10.76 -40.1/18.58 NS -38.81 -67.81/-9.8 0.003 -28.05 -56.47/0.37 NS
SBP (mmHg) -9.71 -17.79/-1.63 0.009 -19.27 -27.25/-11.28 < 0.001 -9.56 -17.38/-1.73 0.008
DBP (mmHg) -5.13 -10.04/-0.21 0.036 -10.84 -15.69/-5.98 < 0.001 -5.71 -10.47/-0.96 0.009
hs-CRP (mg l-1) -0.73 -1.78/0.33 NS -0.73 -1.77/0.3 NS 0.00 -1.05/1.04 NS
C Test post-hoc
0 vs MetS 1 vs MetS 2 vs MetS
MD 95% CI MD p MD 95% CI MD p MD 95% CI MD p
Age (years) -17.89 -22.96/-12.82 < 0.001 -13.87 -18.81/-8.93 < 0.001 -2.45 -7.31/2.41 NS
BMI (kg m-2) -8.90 -11.19/-6.6 < 0.001 -6.82 -9.05/-4.58 < 0.001 -4.65 -6.84/-2.45 < 0.001
WC (cm) -20.51 -25.06/-15.97 < 0.001 -16.16 -20.59/-11.73 < 0.001 -9.83 -14.18/-5.47 < 0.001
FPG (mg dl-1) -25.83 -36.51/-15.16 < 0.001 -22.40 -32.8/-12 < 0.001 -19.42 -29.65/-9.19 < 0.001
FSI (mcU ml-1) -6.25 -10.25/-2.25 < 0.001 -7.28 -11.13/-3.42 < 0.001 -4.31 -8.11/-0.52 0.017
HOMA -2.51 -3.87/-1.15 < 0.001 -2.66 -3.98/-1.35 < 0.001 -1.89 -3.18/-0.6 0.001
HDL-C (mg dl-1) 16.55 11.90/21.21 < 0.001 5.05 0.54/9.56 0.019 7.10 2.65/11.53 < 0.001
TG (mg dl-1) -91.59 -117.14/-66.04 < 0.001 -80.84 -105.72/-55.95 < 0.001 -52.79 -77.27/-28.3 < 0.001
SBP (mmHg) -31.64 -38.66/-24.61 < 0.001 -21.93 -28.77/-15.08 < 0.001 -12.37 -19.1/-5.64 < 0.001
DBP (mmHg) -16.50 -20.77/-12.23 < 0.001 -11.37 -15.53/-7.21 < 0.001 -5.66 -9.75/-1.57 0.002
hs-CRP (mg l-1) -2.03 -2.94/-1.12 < 0.001 -1.30 -2.22/-0.38 0.001 -1.30 -2.19/-0.41 0.001

Statistical evaluation: One way-ANOVA (A) and Bonferroni post-hoc test (B-C).

MetS: Metabolic Syndrome; M: mean; SD: standard deviation; MD: means difference; 95% CI MD: 95% confidence interval of the means difference; BMI: Body mass index; WC: Waist circumference; FPG: fasting plasma glucose; FSI: Fasting serum insulin; HOMA: Homoeostasis Model Assessment; HDL-C: high-density lipoprotein cholesterol; TG: triglycerides; SBP: systolic blood pressure; DBP: diastolic blood pressure; hs-CRP: High-Sensitive C reactive protein; NS: not significant.