Table 2. Characteristics of the population grouped according to the Metabolic Syndrome number of components.
A | MetS number of components | Statistical comparison | |||||||
0 | 1 | 2 | MetS | ||||||
M ± SD | M ± SD | M ± SD | M ± SD | P | |||||
n | 74 | 80 | 84 | 162 | |||||
Age (years) | 35 ± 10 | 39 ± 15 | 51 ± 14 | 53 ± 14 | < 0.001 | ||||
BMI (kg m-2) | 24.23 ± 3.06 | 26.31 ± 5.34 | 28.48 ± 6.86 | 33.12 ± 7.14 | < 0.001 | ||||
WC (cm) | 84 ± 10 | 89 ± 11 | 95 ± 13 | 105 ± 14 | < 0.001 | ||||
FPG (mg dl-1) | 86 ± 8 | 89 ± 8 | 92 ± 11 | 112 ± 44 | < 0.001 | ||||
FSI (mcU ml-1) | 10.14 ± 7.93 | 9.11 ± 5.88 | 12.07 ± 8.54 | 16.38 ± 13.96 | < 0.001 | ||||
HOMA | 2.18 ± 1.81 | 2.02 ± 1.34 | 2.80 ± 2.08 | 4.68 ± 5.25 | < 0.001 | ||||
HDL-C (mg dl-1) | 64 ± 11 | 52 ± 12 | 54 ± 14 | 47 ± 13 | < 0.001 | ||||
TG (mg dl-1) | 78 ± 28 | 89 ± 31 | 117 ± 50 | 170 ± 97 | < 0.001 | ||||
SBP (mmHg) | 103 ± 12 | 113 ± 20 | 122 ± 19 | 135 ± 21 | < 0.001 | ||||
DBP (mmHg) | 65 ± 8 | 70 ± 12 | 76 ± 13 | 81 ± 12 | < 0.001 | ||||
hs-CRP (mg l-1) | 1.70 ± 1.69 | 2.43 ± 2.49 | 2.43 ± 2.44 | 3.73 ± 2.48 | < 0.001 | ||||
B | Test post-hoc | ||||||||
0 vs 1 | 0 vs 2 | 1 vs 2 | |||||||
MD | 95% CI MD | p | MD | 95% CI MD | p | MD | 95% CI MD | p | |
Age (years) | -4.02 | -9.84/1.81 | NS | -15.43 | -21.19/-9.67 | < 0.001 | -11.42 | -17.06/-5.77 | < 0.001 |
BMI (kg m-2) | -2.08 | -4.72/0.55 | NS | -4.25 | -6.85/-1.64 | < 0.001 | -2.17 | -4.72/0.38 | NS |
WC (cm) | -4.35 | -9.57/0.87 | NS | -10.68 | -15.84/-5.52 | < 0.001 | -6.33 | -11.39/-1.28 | 0.006 |
FPG (mg dl-1) | -3.43 | -15.69/8.83 | NS | -6.42 | -18.53/5.7 | NS | -2.98 | -14.86/8.89 | NS |
FSI (mcU ml-1) | 1.03 | -3.56/5.61 | NS | -1.94 | -6.47/2.6 | NS | -2.96 | -7.37/1.45 | NS |
HOMA | 0.16 | -1.4/1.71 | NS | -0.62 | -2.16/0.92 | NS | -0.78 | -2.27/0.72 | NS |
HDL-C (mg dl-1) | 11.50 | 6.16/16.84 | < 0.001 | 9.46 | 4.18/14.74 | < 0.001 | -2.04 | -7.2/3.11 | NS |
TG (mg dl-1) | -10.76 | -40.1/18.58 | NS | -38.81 | -67.81/-9.8 | 0.003 | -28.05 | -56.47/0.37 | NS |
SBP (mmHg) | -9.71 | -17.79/-1.63 | 0.009 | -19.27 | -27.25/-11.28 | < 0.001 | -9.56 | -17.38/-1.73 | 0.008 |
DBP (mmHg) | -5.13 | -10.04/-0.21 | 0.036 | -10.84 | -15.69/-5.98 | < 0.001 | -5.71 | -10.47/-0.96 | 0.009 |
hs-CRP (mg l-1) | -0.73 | -1.78/0.33 | NS | -0.73 | -1.77/0.3 | NS | 0.00 | -1.05/1.04 | NS |
C | Test post-hoc | ||||||||
0 vs MetS | 1 vs MetS | 2 vs MetS | |||||||
MD | 95% CI MD | p | MD | 95% CI MD | p | MD | 95% CI MD | p | |
Age (years) | -17.89 | -22.96/-12.82 | < 0.001 | -13.87 | -18.81/-8.93 | < 0.001 | -2.45 | -7.31/2.41 | NS |
BMI (kg m-2) | -8.90 | -11.19/-6.6 | < 0.001 | -6.82 | -9.05/-4.58 | < 0.001 | -4.65 | -6.84/-2.45 | < 0.001 |
WC (cm) | -20.51 | -25.06/-15.97 | < 0.001 | -16.16 | -20.59/-11.73 | < 0.001 | -9.83 | -14.18/-5.47 | < 0.001 |
FPG (mg dl-1) | -25.83 | -36.51/-15.16 | < 0.001 | -22.40 | -32.8/-12 | < 0.001 | -19.42 | -29.65/-9.19 | < 0.001 |
FSI (mcU ml-1) | -6.25 | -10.25/-2.25 | < 0.001 | -7.28 | -11.13/-3.42 | < 0.001 | -4.31 | -8.11/-0.52 | 0.017 |
HOMA | -2.51 | -3.87/-1.15 | < 0.001 | -2.66 | -3.98/-1.35 | < 0.001 | -1.89 | -3.18/-0.6 | 0.001 |
HDL-C (mg dl-1) | 16.55 | 11.90/21.21 | < 0.001 | 5.05 | 0.54/9.56 | 0.019 | 7.10 | 2.65/11.53 | < 0.001 |
TG (mg dl-1) | -91.59 | -117.14/-66.04 | < 0.001 | -80.84 | -105.72/-55.95 | < 0.001 | -52.79 | -77.27/-28.3 | < 0.001 |
SBP (mmHg) | -31.64 | -38.66/-24.61 | < 0.001 | -21.93 | -28.77/-15.08 | < 0.001 | -12.37 | -19.1/-5.64 | < 0.001 |
DBP (mmHg) | -16.50 | -20.77/-12.23 | < 0.001 | -11.37 | -15.53/-7.21 | < 0.001 | -5.66 | -9.75/-1.57 | 0.002 |
hs-CRP (mg l-1) | -2.03 | -2.94/-1.12 | < 0.001 | -1.30 | -2.22/-0.38 | 0.001 | -1.30 | -2.19/-0.41 | 0.001 |
Statistical evaluation: One way-ANOVA (A) and Bonferroni post-hoc test (B-C).
MetS: Metabolic Syndrome; M: mean; SD: standard deviation; MD: means difference; 95% CI MD: 95% confidence interval of the means difference; BMI: Body mass index; WC: Waist circumference; FPG: fasting plasma glucose; FSI: Fasting serum insulin; HOMA: Homoeostasis Model Assessment; HDL-C: high-density lipoprotein cholesterol; TG: triglycerides; SBP: systolic blood pressure; DBP: diastolic blood pressure; hs-CRP: High-Sensitive C reactive protein; NS: not significant.