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Protocol scheme of the study. SNx, subtotal nephrectomy of the 5/6 or sham operation; SNx 1 indicates first part of the surgery; SNx 2, second part of the surgery; CrCl, creatinine clearance. MRI was performed before the first injection, and then once a week (W). Twenty injections of gadodiamide, 0.6 mmol Gd/kg/injection, were distributed over 5 weeks, leading to a cumulative dose of 12 mmol Gd/kg. Killing was performed 6 days after the last injection.
