Figure 4. Striatal SDH activity after acute 3-NP injection.
L-12/15 LO null mutant mice (−/−,) and their wild type littermates (+/+) were injected with 200 mg/kg 3-NP or saline (n = 3 each). Two hr later, SDH activities were measured as described in methods. Data were normalized to each genotype’s control group (− 3-NP) and expressed as mean + SEM. Significant between-group differences (*;+/− 3-NP treatment), but no within-group (i.e., genotype) differences were found by two-way ANOVA followed by Bonferroni’s t test.