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. 2017 Apr 6;12(4):e0175183. doi: 10.1371/journal.pone.0175183

Table 3. Association analysis for QFT positivity among smokers.

Variables N % p for χ2 test Adjusted OR#(95% CI)
Gender
    Female 41/131 31.30 0.528 Reference
    Male 1427/4961 28.76 0.91 (0.62.1.35)
Age (years)
    5–19 4/46 8.70 <0.001 Reference
    20–29 58/506 11.46 1.30 (0.45,3.75)
    30–39 108/590 18.31 1.72 (0.58,5.09)
    40–49 331/1285 25.76 2.27 (0.76,6.72)
    50–59 367/1139 32.22 2.74 (0.91,8.19)
    60–69 394/1033 38.14 3.25 (1.08,9.79)
    ≥70 206/493 41.78 3.53 (1.15, 10.85)
Education level
    Primary school or lower 731/2179 33.55 <0.001
    Middle school 560/2162 25.90
    High school 155/643 24.11
    College or higher 22/108 20.37
Household per capita income (RMB)
    <6000 924/3108 29.74 0.076
    ≥6000 544/1984 27.42
BMI (kg/m2)
    18.5–24.0 814/2766 29.43 0.520
    <18.5 71/276 25.72
    24.0–28.0 436/1515 28.78
    ≥28.0 147/535 27.48
Alcohol drinking
    No 732/2358 31.04 0.001
    Yes 736/2734 26.92
TB contact history
    No 1381/4862 28.40 0.002 Reference
    Yes 87/228 38.16 1.48 (1.12,1.97)
History of T2DM
    No 1352/4751 28.46 0.029
    Yes 116/341 34.02
Smoking status
    Former smoker 101/352 28.69 0.953
    Current smoker 1367/4740 28.84
Cigarette type
    Without filter 108/324 33.33 0.064
    With filter 1360/4768 28.52
Onset of cigarette smoking (years)
    <18 279/927 30.10 0.346
    ≥18 1189/4165 28.55
Duration of smoking (years)
    ≤10 96/753 12.75 <0.001 Reference
    10–20 199/891 22.33 p for trend<0.001 1.45 (1.02, 2.06)
    20–30 366/1305 28.05 1.65 (1.14, 2.40)
    30–40 392/1138 34.45 1.90(1.28, 2.82)
    40–50 294/726 40.50 2.09 (1.36, 3.19)
    >50 121/279 43.37 2.26 (1.38, 3.69)
Number of cigarettes per day
    1–5 126/507 24.85 0.009
    5–10 182/683 26.65 p for trend<0.001
    10–19 525/1912 27.46
    ≥20 635/1990 31.91

Abbreviations: BMI = body mass index; CI = confidence interval; OR = odds ratio; QFT = QuantiFERON-TB Gold In-Tube; T2DM = type 2 diabetes mellitus; TB = tuberculosis.

Indeterminate results had been excluded from the analysis. Sum might not always be in total because of missing data.

# Adjusted for variables with p < 0.05 in univariate analysis by stepwise selection. Sex and age kept in the model.