Table 8. Formation of DNA-protein crosslinks in intestine of rats treated with a single oral dose of NaNO₂.

	DNA-protein crosslinks % a	DNA-protein crosslinks coefficient b
Control	2.8 ± 0.16	1.0
20 mg/kg body weight	3.36 ± 0.18	1.2
40 mg/kg body weight	5.82 ± 0.30*	2.1
60 mg/kg body weight	8.12 ± 0.42*	2.9
75 mg/kg body weight	9.41 ± 0.47*	3.36

^a DNA-protein crosslinks / total DNA

^b DNA-protein crosslinks (%) in NaNO₂ treated animals / DNA-protein crosslinks (%) in control animals

Results are mean ± standard error of six different samples.

^* Significantly different at p< 0.05 from control.