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. 2017 Apr 6;12(4):e0175312. doi: 10.1371/journal.pone.0175312

Fig 1. NPS reduces duodenal bicarbonate secretion and mucosal net fluid secretion, dependence on NO activity.

Fig 1

A) Continuous i.v. infusion of NPS at 8–833 pmol·kg-1·min-1 reduced duodenal bicarbonate secretion and C) decreased duodenal mucosal net fluid secretion. B & D) Pre-treatment with L-NAME abolished the effects of NPS. # indicates a significant (P<0.05) reduction compared with baseline (0–30 min) in the same group. * indicates significantly (P<0.05) higher compared with baseline (0–30 min) in the same group. § indicates a significant (P<0.05) reduction compared to time-matched control animals.