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Endogenous epoxide:diol ratios for (A) 8,9-EET/8,9-DHET, (B) 11,12-EET/11,12-DHET, (C) 14,15-EET/14,15-DHET, (D) 9,10-EpOME/9,10-DiHOME, (E) 12,13-EpOME/12,13-DiHOME, (F) 17,18-EpETE/17,18-DHET, and (G) 19,20-EpDPE/19,20-DiHDPA were determined in the heart, lung, skin, and plasma by LC-MS/MS in Ephx3-/- and WT mice (n = 3–10, p = NS).
