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. 2017 Apr 6;12(4):e0175451. doi: 10.1371/journal.pone.0175451

Table 1. Experimental design of the study.

The whole study comprised of 23 Sprague Dawley animals, matched in age and weight. All rodents got a thermic cauterization in order to elevate their IOP on the left eye. For each animal the right eye served as a contralateral control.

Exp. Group Animal number IOP elevation (OS) Crystallin injection Sacrificed after stated week of elevated IOP
Time point 1 8 + - 3
Time point 2 7 + - 7
β-crystallin B2 1 4 + + 7
β-crystallin B2 2 4 + + 3