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. 2017 Mar 23;13(3):e1005449. doi: 10.1371/journal.pcbi.1005449

Fig 2. Overrepresentation of interactions between coding drivers and transcriptional drivers in the protein interactome.

Fig 2

The significance of enrichment was estimated as the observed-to-expected ratio of the number of interactions for each TD category grouped by the recurrence level as combined for breast and liver cancer. The expected number was obtained by permuting the links or nodes of the network. The permutation was repeated 1,000 times. (A) Enrichment of interactions between the TDs and CGC CDs. (B) Enrichment of interactions between the TDs and 20/20 CDs.