Table 1.
Recipient, donor, and kidney transplant characteristics
| Characteristics, N (%) (unless otherwise specified) | Categories | ||||
|---|---|---|---|---|---|
| >30 kg (D>R) | 10–30 kg (D>R) | <10 kg (D=R) | 10–30 kg (D<R) | >30 kg (D<R) | |
| n=15,002 (13.0) | n=24,903 (21.6) | n=35,495 (30.8) | n=26,071 (22.6) | n=13,653 (11.9) | |
| Donor factors | |||||
| Donor type | |||||
| SCD | 10,363 (69.1) | 17,727 (71.2) | 25,256 (71.2) | 18,659 (71.6) | 10,110 (74.0) |
| ECD | 2831 (18.9) | 4674 (18.8) | 6738 (19.0) | 4823 (18.5) | 2060 (15.1) |
| DCD | 1808 (12.0) | 2502 (10.0) | 3501 (9.9) | 2589 (9.9) | 1483 (10.9) |
| Mean age ±SD, yr | 42.8±12.8 | 42.2±13.7 | 41.9±14.2 | 41.7±14.4 | 40.6±14.2 |
| Sex (M) | 10,592 (70.6) | 16,811 (67.5) | 21,374 (60.2) | 13,466 (51.6) | 6153 (45.1) |
| Mean height ±SD, m | 1.77±0.1 | 1.74±0.1 | 1.72±0.1 | 1.70±0.1 | 1.68±0.1 |
| Median donor weight (Q1–Q3), kg | 108.9 (97.5–122.5) | 88.2 (79.4–99.0) | 77.2 (69.0–87.0) | 70.0 (62.0–79.4) | 64.7 (56.7–73.0) |
| Diabetes | 1905 (12.8) | 1949 (7.9) | 2177 (6.2) | 1294 (5.0) | 560 (4.1) |
| BMI (Q1–Q3), kg/m2 | 34.7 (30.6–39.7) | 28.9 (25.8–32.4) | 25.9 (23.4–29.0) | 24.2 (21.8–26.9) | 22.8 (20.4–25.4) |
| Recipient factors | |||||
| Mean age ±SD, yr | 51.5±14.1 | 52.0±13.5 | 52.9±12.9 | 53.4±12.2 | 52.1±11.6 |
| Male sex | 6811 (45.4) | 12,946 (52.0) | 21,972 (61.9) | 18,327 (70.3) | 10,837 (79.4) |
| Mean height ±SD, m | 1.65±0.1 | 1.67±0.1 | 1.70±0.1 | 1.73±0.1 | 1.78±0.1 |
| Median recipient weight (Q1–Q3), kg | 64.0 (54.9–74.4) | 69.3 (60.6–79.0) | 77.6 (68.9–87.1) | 89.3 (80.7–98.5) | 107.3 (97.9–117.9) |
| Diabetes | 4026 (26.9) | 7293 (29.4) | 11,738 (33.2) | 9981 (38.4) | 5841 (42.8) |
| Previous kidney transplant | 2433 (16.4) | 3735 (15.0) | 4531 (12.8) | 2851 (10.9) | 1281 (8.6) |
| Dialysis vintage >4 yr | 5731 (39.0) | 9369 (38.4) | 12,816 (37.0) | 8973 (35.2) | 4813 (36.0) |
| BMI (Q1–Q3), kg/m2 | 23.4 (20.8–26.6) | 24.7 (22.0–27.9) | 26.7 (24.0–30.0) | 29.8 (26.8–33.0) | 34.2 (31.0–37.4) |
| Surgical and immunologic factors | |||||
| Median cold ischemic time (IQR), h | 18.2 (12.0–23.0) | 17.9 (11.8–23.0) | 17.9 (11.6–23.0) | 17.8 (11.7–23.0) | 17.8 (11.5–22.9) |
| Peak PRA <20 | 9368 (63.6) | 15,939 (65.2) | 23,987 (69.0) | 18,397 (72.1) | 10,060 (75.3) |
| Peak PRA 20–80 | 3039 (20.6) | 4923 (20.2) | 6515 (18.8) | 4482 (17.6) | 2117 (15.9) |
| Peak PRA >80 | 2334 (15.8) | 3569 (14.6) | 4238 (12.2) | 2634 (10.3) | 1182 (8.8) |
| Induction therapy (ATG) | 6752 (45.0) | 10,849 (43.6) | 15,187 (42.8) | 10,945 (42.0) | 6010 (44.0) |
| Donor and recipient factors | |||||
| HLA mismatches | |||||
| 0MM | 1586 (10.6) | 2704 (10.9) | 3728 (10.6) | 2645 (10.2) | 1391 (10.3) |
| 1MM | 347 (2.3) | 651 (2.6) | 849 (2.4) | 667 (2.6) | 319 (2.4) |
| 2MM | 718 (4.8) | 1151 (4.7) | 1733 (4.9) | 1216 (4.7) | 652 (4.8) |
| 3MM | 2017 (13.5) | 3285 (13.3) | 4614 (13.1) | 3519 (13.6) | 1748 (12.9) |
| 4MM | 3726 (24.9) | 6265 (25.3) | 8899 (25.3) | 6341 (24.5) | 3473 (25.6) |
| 5MM | 4379 (29.3) | 7090 (28.7) | 10,222 (29.0) | 7668 (29.6) | 3964 (29.3) |
| 6MM | 2167 (14.5) | 3594 (14.5) | 5187 (14.7) | 3826 (14.8) | 2000 (14.8) |
| Absolute weight difference (Q1–Q3), kg | 41.7 (35.0–52.2) | 18.6 (14.0–23.6) | 0.0 (−5.0–4.9) | −18.6 (−23.7–−14.1) | −40 (−48.7–−34.5) |
| MDMR | 4805 (32.0) | 9057 (36.4) | 13,948 (39.3) | 9880 (37.9) | 5068 (37.1) |
| FDFR | 2404 (16.0) | 4203 (16.9) | 6097 (17.2) | 4158 (16.0) | 1731 (12.7) |
| MDFR | 5787 (38.6) | 7754 (31.1) | 7426 (20.9) | 3586 (13.8) | 1085 (8.0) |
| FDMR | 2006 (13.4) | 3889 (15.6) | 8024 (22.6) | 8447 (32.4) | 5769 (42.2) |
Proportion missing: Recipient diabetes (0.31%); donor diabetes (0.47%); DCD (0.01%); dialysis vintage (2.15%); HLA mismatch (0.68%); peak PRA (1.66%); cold ischemic time (7.77%). D>R, donor greater than recipient; D=R, donor equal to recipient; D<R, donor less than recipient; SCD, standard criteria donor; ECD, expanded criteria donor; DCD, donation by cardiac death; M, male; Q1, quarter 1; Q3, quarter 3; BMI, body mass index; IQR, interquartile range; PRA, panel reactive antibody; ATG, antithymoglobulin; HLA, human leukocyte antigen; MM, mismatch; MDMR, male donor/male recipient; FDFR, female donor/female recipient; MDFR, male donor/female recipient; FDMR, female donor/male recipient.