Table 2.
Relative hazards for death-censored graft loss using donor/recipient absolute weight difference and donor/recipient sex pairing
| Donor-Recipient Pairing | HR (95% CI) |
|---|---|
| Weight-unadjusted | |
| >30 kg (D>R) | 1.00 (0.96 to 1.05) |
| 10–30 kg (D>R) | 0.97 (0.93 to 1.00) |
| <10 kg (D=R) | Ref |
| 10–30 kg (D<R) | 1.11 (1.07 to 1.15) |
| >30 kg (D<R) | 1.28 (1.22 to 1.34) |
| Weight-adjusteda | |
| >30 kg (D>R) | 1.00 (0.94 to 1.04) |
| 10–30 kg (D>R) | 0.97 (0.93 to 1.01) |
| <10 kg (D=R) | Ref |
| 10–30 kg (D<R) | 1.10 (1.05 to 1.13) |
| >30 kg (D<R) | 1.22 (1.16 to 1.28) |
| Sex-unadjusted | |
| MDMR | Ref |
| FDFR | 1.12 (1.08 to 1.16) |
| MDFR | 1.00 (0.96 to 1.04) |
| FDMR | 1.22 (1.18 to 1.27) |
| Sex-adjustedb | |
| MDMR | Ref |
| FDFR | 1.08 (1.02 to 1.14) |
| MDFR | 1.08 (1.03 to 1.13) |
| FDMR | 1.10 (1.05 to 1.15) |
HR, hazard ratio; 95% CI, 95% confidence interval; D>R, donor greater than recipient; D=R, donor equal to recipient; Ref, reference; D<R, donor less than recipient; MDMR, male donor/male recipient; FDFR, female donor/female recipient; MDFR, male donor/female recipient; FDMR, female donor/male recipient.
Adjusted for: donor factors: type (expanded criteria donor versus standard criteria donor), donation by cardiac death, sex, race, height, diabetes status, hepatitis C; surgical & immunologic factors: number of human leukocyte antigen mismatches, peak panel reactive antibody, induction therapy, cold ischemia time; recipient factors: diabetes, age, cause of ESRD, sex, race, height, previous kidney transplant, dialysis vintage.
Adjusted for: donor factors: type (expanded criteria donor versus standard criteria donor), donation by cardiac death, race, height, weight, diabetes status, hepatitis C; surgical & immunologic factors: number of human leukocyte antigen mismatches, peak panel reactive antibody, induction therapy, cold ischemia time; recipient factors: diabetes, age, cause of ESRD, race, height, weight, previous kidney transplant, dialysis vintage.