Table 2.
CD27, programmed death 1 (PD‐1) and CD57 expression on CD28null T cells in the peripheral blood and lymph node
| PB (n = 38) | LN (n = 33) | P | |
|---|---|---|---|
| CD4+ T cells | |||
| CD28+CD27+ (%) | 87·4 (81·5–94·3) | 93·8 (91·6–96·1) | < 0·001 |
| CD28nullCD27– (%) | 1·1 (0·2–7·5) | 0·3 (0·1–0·6) | < 0·001 |
| CD28+PD–1– (%) | 78·5 (71·0–84·0) | 74·2 (65·8–81·6) | 0·077 |
| CD28nullPD–1+ (%) | 1·0 (0·3–7·3) | 0·4 (0·3–0·9) | 0·004 |
| CD28+CD57– (%) | 96·7 (90·1–98·7) | 97·4 (96·0–98·2) | 0·063 |
| CD28nullCD57+ (%) | 0·8 (0·1–5·9) | 0·1 (0·0–0·2) | < 0·001 |
| CD8+ T cells | |||
| CD28+CD27+ (%) | 54·8 (36·7–73·7) | 89·8 (84·1–92·6) | < 0·001 |
| CD28nullCD27– (%) | 28·7 (10·8–49·3) | 1·9 (1·0–2·6) | < 0·001 |
| CD28+PD–1– (%) | 43·1 (25·9–57·5) | 63·2 (49·5–75·1) | < 0·001 |
| CD28nullPD–1+ (%) | 12·4 (6·9–18·4) | 2·4 (1·6–5·1) | < 0·001 |
| CD28+CD57– (%) | 56·2 (37·5–73·9) | 87·3 (80·2–89·7) | < 0·001 |
| CD28nullCD57+ (%) | 26·6 (13·4–39·1) | 1·5 (1·0–2·3) | < 0·001 |
Data are presented as medians (interquartile range). PB = peripheral blood; LN = lymph node.