Figure 2.
Sequence alignment of OspA protein from three prevalent Borrelia genospecies including B. burgdorferi B31, B. afzelii BO23 and B. garinii PBi. Non-conserved amino acids that differ among species are in blue font. The three surface loops in the LA-2 recognition epitope, which were subjected to mutagenesis in this study, are highlighted in yellow.
