Table 1. Incidence of FH gene mutant alleles in autosomal dominant FH.

Genetic hypercholesterolemia	FH classification	FH gene mutation	Homozygote (n), (%)	Heterozygote (n), (%)	Total mutant alleles (n), (%)
Autosomal dominant hypercholesterolemia (ADH)	ADH1	LDL-R	69 (84.1%)	757 (71.8%)	826 (72.6%)
	ADH2	APO-B	0 (0%)	0 (0%)	0 (0%)
	ADH3	PCSK9	13 (15.9%)	62 (5.9%)	75 (6.6%)
	ADH4	STAP1 *	0 (0%)	0 (0%)	0 (0%)
Unknown			0 (0%)	236 (22.4%)	236 (20.8%)
Total			82 (100%)	1055 (100%)	1137 (100%)

FH genes: LDL-R gene, apolipoprotein B-100 (Apo-B) gene, PCSK9 gene and STAP1

STAP1*: not studied