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editorial
. 2017 Mar 1;24(3):258–261. doi: 10.5551/jat.Ed064

Table 1. Recent (published in 2013 or later) epidemiological findings of blood pressure's association with cardiovascular disease in the older individuals.

Study name, year published Singapore Chinese Health Study, 20168) Costa Rican CRELES study, 201610) Northern Manhattan Study (US), 20169) Taipei City Geriatric Health Examination Database, 201511) Strobe-Compliant Study (China), 201512) Kangwha cohort study (Korea), 201513) REGARDS study (US), 201414) TGLS Study (Iran), 201415) LSUHLS (US), 201316)
Baseline year 1993–1998 2004–2006 1993–2001 2006 2004–2006 1985 2003–2007 1999–2001 1999–2009
Follow-up, years max: 10 mean: 5.1 median: 13 max: 4 median: 4.8 max: 23.8 median: 4.5 median: 10 mean: 6.0
Age range or mean age, years 48–85, 63.0 ± 7.8 60-, 76 ± 10.2 60-, 72 ± 8 65-, 73.0 60-, 69.5 ± 7.0 55-, 66.7 ± 8.0 55-, 79.3 ± 3.7 [for those aged ≥ 75] 60-, 65.8 30–94
Sample size 30,692 (n of age ≥ 60 = 19,110) 2,346 1,750 77,389 5,006 6,294 (n of age ≥ 65 = 3,387) 9,787 (n of age ≥ 75 = 1,839) 1,845 30,154
Inclusion criteria related to histories none those without stroke, heart disease or cancer those without stroke, DM, and CKD none those with HT those taking antihypertensive medications those without CVD DM patients without a history of CHD or stroke
Women (%) 55.7% 57.2% 63.0% 49.2% 51.4% 57.2% 63.1% [for those aged ≥ 75] 49.6% 64%
Baseline SBP/DBP, mmHg SBP: <100: 2.9%
110–119: 20.1%,
120–139: 35.4%,
140–159: 26.4%,
160–179: 11.1%,
≥ 180: 4.1%
SBP: 140–159: 31%*,
≥ 160: 21.7%*;
DBP <70: 17.6%*,
≥ 90: 22.0%*
SBP: <140: 43%,
140–149: 20%,
≥ 150: 37%
Men:
SBP: 135.0 ± 19.0/DBP: 76.4 ± 11.5,
Women:
SBP: 135.7 ± 20.1/DBP: 75.8 ± 11.4
SBP: 162.5 ± 21.3/DBP: 91.7 ± 12.9 SBP: 148.5 ± 31.7 [for total sample] Isolated Systolic Hypertension, 25.7% [for those aged ≥ 75] SBP: 136.0/DBP: 80.1 SBP: 145/DBP: 80
Outcome CVD mortality CVD mortality Stroke incidence CVD mortality CVD mortality, CHD and stroke incidence CVD mortality CVD incidence CVD incidence CHD incidence
Reference BP category SBP 120–139 SBP < 140 SBP < 140 SBP < 120 and DBP < 80 SBP < 130 DBP 85–89 SBP: 100–119 SBP < 120 SBP < 120 and DBP < 80 SBP: 130–139 and DBP: 80–89
BP categories significantly associated with increased outcome SBP ≥ 180;
SBP < 100 in those with CVD history
SBP ≥ 160 SBP 140–149 SBP ≥ 160 DBP ≥ 100 SBP ≥ 160 DBP ≥ 100 SBP ≥ 180 (in those aged ≥ 65) SBP ≥ 150 (in those aged ≥ 75) SBP ≥ 140, DBP ≥ 90 or on antihypertensive medications (in those aged ≥ 60) < 110/65 (in those aged 60–94)

CRELES indicates Costa Rican Longevity and Healthy Aging Study; US, United States; DM, diabetes mellitus; CKD, chronic kidney disease; HT, hypertension; SBP, systolic blood pressure; DBP, diastolic blood pressure; CVD, cardiovascular disease; CHD, coronary heart disease; BP, blood pressure.

*

The percentages are based on the number of total participants interviewed at baseline. Those of the analyzed sample were not available.

REGARDS indicates REasons for Geographic and Racial Differences in Stroke; TLGS, Tehran Lipid and Glucose Study; LSUHLS, Louisiana State University Hospital-Based Longitudinal Study. For the other abbreviations, please see the first page of Table 1.