Table 2. Relative risk factors of skin AF in type 1 diabetes.
| Univariate |
Multivariate |
|||||
|---|---|---|---|---|---|---|
| r | p | β | p | |||
| Age (year) | 0.470 | <0.001 | 0.412 | <0.001 | ||
| Gender (male) | 0.213 | 0.029 | NI | |||
| Duration of diabetes (years) | 0.248 | 0.003 | NI | |||
| Smoking | 0.332 | <0.001 | 0.225 | 0.012 | ||
| BMI (kg/m2) | 0.170 | NS | ||||
| Systolic BP (mmHg) | 0.173 | NS | ||||
| Diastolic BP (mmHg) | 0.153 | NS | ||||
| GGT (U/L) | 0.320 | <0.001 | NI | |||
| Glucose (mg/dL) | 0.118 | NS | ||||
| HbA1c (%) | 0.217 | 0.026 | NI | |||
| TG (mg/dL) | 0.130 | NS | ||||
| LDL-C (mg/dL) | 0.106 | NS | ||||
| HDL-C (mg/dL) | −0.072 | NS | ||||
| UA (mg/dL) | 0.246 | 0.011 | NI | |||
| eGFR (ml/min/1.73 m2) | −0.246 | 0.011 | NI | |||
| R2 | 0.269 | |||||
The threshold of statistical significance was defined as p <0.05.
Gender: male = 1, female = 0, Smoking: yes = 1, no = 0.
Stepwise multivariate regression analysis was performed to determine the predictors of skin AF. The significant (p <0.05) variables in Pearson's univariate analysis were selected for multivariate regression analysis.
Abbreviations: β, partial regression coefficient; NS, not significant; NI, not included in the model; Gender: male = 1, female = 0, Smoking: yes = 1, no = 0; BMI, body mass index; BP, blood pressure; GGT, κ-glutamyltransferase; HbA1c, glycated hemoglobin A1c; GA, glycoalbumin; TG, serum triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; UA, uric acid; eGFR, estimated glomerular filtration rate.