Table 3. Change of mean pH and % time of gastric pH above 4.0 in relation to CYP2C19 phenotypes.

Dosing	PM (n = 8)	IM (n = 8)	EM (n = 8)	P value*
Single dosing
Change of mean pH	2.84 ± 0.48	0.78 ± 0.70	0.71 ± 0.78	0.001
% time gastric pH above 4.0	66.83 ± 14.06	21.43 ± 7.79	19.66 ± 17.07	0.001
Multiple dosing
Change of mean pH	3.45 ± 0.72	2.19 ± 0.74	1.81 ± 1.02	0.006
% time gastric pH above 4.0	78.99 ± 15.79	53.90 ± 12.10	42.23 ± 19.03	0.005

Variables are given as mean ± standard deviation.

PM = poor metabolizer, IM = internal medicine, EM = emergency medicine.

^*Kruskal-Walis test.