Table 1. OIs and seropositive rates for GBS (serotypes Ia, Ib, and III) in various IVIG products and in Korean infants.
| Variables | GMIs (95% CIs) | Seropositive rate, No. (%) | ||||
|---|---|---|---|---|---|---|
| Serotype Ia | Serotype Ib | Serotype III | Serotype Ia | Serotype Ib | Serotype III | |
| IVIG (No.) | ||||||
| Korea-A (6) | 778 (672–905) | 525 (504–547) | 1,614 (1,428–1,823) | - | - | - |
| Korea-B (10) | 1,195 (820–1,742) | 546 (528–565) | 1,948 (1,569–2,420) | - | - | - |
| Korean products (16) | 1,018 (786–1,319) | 538 (524–553) | 1,816 (1,567–2,103) | - | - | - |
| Total (19) | 1,185 (900–1,560) | 607 (531–693) | 1,981 (1,690–2,322) | - | - | - |
| Infants' sera, mon (No.) | ||||||
| 0–2 (22) | 2.7 (2.0–3.7) | 6.2 (3.2–11.8) | 6.4 (3.1–13.5) | 4 (18.2) | 9 (40.9) | 8 (36.4) |
| 3–5 (14) | 2.3 (1.8–3.0) | 3.3 (1.7–6.5) | 3.8 (1.8–8.0) | 1 (7.1) | 2 (14.3) | 3 (21.4) |
| 6–8 (34) | 2.7 (2.0–3.6) | 7.3 (3.5–15.3) | 7.7 (3.8–15.7) | 5 (14.7) | 11 (32.4) | 12 (35.3) |
| 9–11 (28) | 3.5 (2.4–5.2) | 14.7 (6.5–33.2) | 22.0 (8.4–57.7) | 8 (28.6) | 16 (57.1) | 15 (53.6) |
| Total (98) | 2.7 (2.3–3.2) | 6.1 (4.2–8.9) | 6.9 (4.6–10.5) | 18 (18.4)* | 38 (38.8) | 38 (38.8) |
OIs = opsonization indices, GBS = group B streptococcus, CIs = confidence intervals, IVIG = intravenous immunoglobulin, GMIs = geometric mean indices.
*Significant difference in the seropositive rates based on Cochran's Q test (P = 0.002).