Figure 4.

Understanding phage diversity, community interactions and chemical profiles using meta-omics approach. Genomics elucidates the phage diversity, abundance, probable functional features while transcriptomics gives an insight about the actively expressed genes in a community. Proteomics suggests the phage structural proteins, its functions and the proteins responsible for interaction between phage and host. Metabolomics advocates the metabolites produced by hosts in presence and absence of phage infection, alterations in regulation and metabolic profiles after infection. SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; ESI-MS, electron spray ionization–mass spectroscopy; LC-MS, liquid chromatography–mass spectrometry; MALDI-MS, matrix-assisted laser ionization and deionization; NMR, nuclear magnetic resonance; NIMS, nanostructure initiator MS.