Table 1.
Particle characterization of virosomes and liposomes.
| Samples | DLS |
NTA | |
|---|---|---|---|
| Size ± SD (nm) | PDI ± SD | Size ± SD (nm) | |
| Virosome-Atto647 | 95.1 ± 1.0 | 0.035 ± 0.004 | 76.9 ± 0.4 |
| Virosome-Atto647-OVA | 101.0 ± 5.8 | 0.041 ± 0.010 | 84.9 ± 0.5 |
| Liposome-Atto647 | 92.6 ± 2.5 | 0.027 ± 0.002 | 79.1 ± 0.8 |
| Liposome-Atto647-OVA | 101.3 ± 8.4 | 0.025 ± 0.015 | 84.0 ± 0.4 |
Virosomes and liposomes coupled either to the fluorochrome Atto647 and/or model protein OVA were analyzed by dynamic light scattering (DLS; Zetasizer Nano S) or by nanoparticle tracking analysis (NTA; NanoSight NS300). Data represent three formulations of virosomes and liposomes with their average modal size (median ± SD, n = 3) and the polydispersity index (PDI).