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. 2016 Dec 29;31(5):354–360. doi: 10.1038/jhh.2016.86

Table 5. Clinical characteristic of HP patients with and without beta-blockers.

  Without beta-blockers (n=70) With beta-blockers (n=70) P-value
Age (yr) 58.29±7.41 59.16±7.20 0.482
Male gender (n, %) 28/70 (40.0%) 30/70 (42.9%) 0.731
BMI (kg m−2) 25.85±3.25 24.51±3.61 0.022
Smoker (n, %) 21/70 (30.0%) 24/70 (34.3%) 0.587
Manual labour (n, %) 46/70 (65.7%) 44/70 (62.9%) 0.724
Education (n, %)     0.316
 Primary school and below (n, %) 7/70 (10.0%) 5/70 (7.1%)  
 Middle school (n, %) 18/70 (25.7%) 28/70 (40.0%)  
 High school (n, %) 35/70 (50.0%) 27/70 (38.6%)  
 University and above (n, %) 10/70 (14.3%) 10/70 (14.3%)  
CAD (n, %) 12/70 (18.6%) 33/70 (47.1%) 0.000
DM (n, %) 17/70 (24.3%) 10/70 (14.3%) 0.134
Dyslipidemia (n, %) 60/70 (85.7%) 56/70 (80.0%) 0.370
Creatinine (μM) 66.73±13.83 65.63±15.61 0.659
CHOL (mM) 4.78±0.94 4.71±1.19 0.706
TG (mM) 2.11±1.50 2.18±1.92 0.822
LDL-c (mM) 2.88±0.77 2.80±1.15 0.637
HDL-c (mM) 1.06±0.28 1.09±0.35 0.514
HR before Ex (b.p.m.) 81.41±11.92 80.41±12.57 0.630
Peak HR (b.p.m.) 140.91±6.84 140.00±7.50 0.452
HR1(b.p.m.) 114.59±9.68 114.49±10.59 0.954
HRR1 (b.p.m.) 26.33±7.06 25.51±8.62 0.542
HRR1 ⩽24  b.p.m. (%) 31/70 (44.3%) 34/70 (48.6%) 0.611
HR2 (b.p.m.) 97.06±12.49 95.31±14.14 0.441
HRR2 (b.p.m.) 43.86±11.11 44.69±11.92 0.671
HRR2 ⩽42  b.p.m. (%) 31/70 (44.3%) 22/70 (31.4%) 0.865
HR3 (b.p.m.) 90.73±12.35 89.77±12.86 0.654
HRR3 (b.p.m.) 50.19±11.18 50.23±11.31 0.982
HR4 (b.p.m.) 87.77±11.53 87.49±12.24 0.887
HRR4 (b.p.m.) 53.14±10.44 52.51±11.21 0.732
HR5 (b.p.m.) 85.99±11.43 86.77±12.55 0.699
HRR5 (b.p.m.) 54.93±10.51 53.23±11.08 0.353
SBP before Ex (mm Hg) 131.36±15.16 129.63±13.52 0.478
DBP before Ex (mm Hg) 81.37±8.93 80.16±8.95 0.423
SBP peak (mm Hg) 181.36±19.98 168.00±18.62 0.069
DBP peak (mm Hg) 82.06±11.75 78.07±10.86 0.345
SBP at 1 min post Ex (mm Hg) 154.71±22.54 144.90±19.05 0.062
DBP at 1 min post Ex (mm Hg) 80.17±9.80 78.52±10.50 0.510
SBP at 5 min post Ex (mm Hg) 136.20±27.88 134.58±24.35 0.736
DBP at 5 min post Ex (mm Hg) 81.50±15.95 78.08±14.14 0.433
Time for Ex (minute) 4.14±1.61 4.35±1.83 0.478
Exercise tolerance (Mets) 6.16±1.56 6.57±1.94 0.177
Ejection fraction 0.63±0.06 0.62±0.07 0.325
Medication      
 Aspirin use (n, %) 39/70 (55.7%) 51/70 (72.9%) 0.034
 Statin use (n, %) 47/70 (67.1%) 51/70 (72.9%) 0.461
 ACEI use (n, %) 20/70 (28.6%) 19/70 (27.1%) 0.850
 ARBs use (n, %) 27/70 (38.6%) 14/70 (20.0%) 0.016
 CCB use (n, %) 57/70 (81.4%) 36/70 (51.4%) 0.000
 Diuretics use (n, %) 9/70 (12.9%) 3/70 (4.3%) 0.070

Abbreviations: ACEI, angiotensin-converting enzyme inhibitor; ARBs, angiotensin receptor blocker; BP, blood pressure; BMI, body mass index; CAD, coronary artery disease; CCB, calcium channel blocker; CHOL, cholesterol; DBP, diastolic blood pressure; DM, diabetes mellitus; Ex, treadmill exercise; HDL-c, high density lipoprotein cholesterol; HP, hypertensive; HR, heart rate; HRn, heart rate at n minute post exercise; HRR, heart rate recovery; HRRn, heart rate recovery at n minute post exercise; LDL-c, low density lipoprotein cholesterol; Mets, metabolic equivalents (1MET=3.5 ml kg−1 per minute of oxygen consumption); SBP, systolic blood pressure; TG, triglyceride; yr, year.