Pathway response with maximization of metabolic function, ‘GBM_BM’ as the objective. Flow of flux through the different reactions of a glycolysis, b pentose phosphate pathway, c cysteine metabolism, d TCA cycle; while maximizing the metabolic function, GBM_BM, for glioblastoma growth. A positive flux shows progression of reaction in forward direction and a negative flux implies flow of flux in reverse direction