Fig. 8.

Single and double reaction knockout predictions. The results of single and double reaction knockout predictions are summarized. a, b Single and double knockout reaction classifications, respectively. The predictions are classified in five categories: (1) lethal (inhibition = 100 %), (2) partial growth reducers (100 % < inhibition < 80 %), (3) marginal growth reducers (80 % < inhibition < 20 %), (4) sub-marginal growth reducers (20 % < growth < 0 %), (5) null reducers (inhibition = 0 %), with the percentage inhibition imposed by them being indicated in the parentheses