Fig. 8.

A model for the cricket circadian clock. The clock includes two negative feedback loops, one for Gb’per/Gb’tim like in Drosophila and the other for Gb’cry2. The latter is comprised of two Gb’cry2 variants, Gb’cry2c and Gb’cry2f, or Gb’cry2c and Gb’cry1, and their product proteins that form a complex to suppress the transcription mediated by Gb’CLK/Gb’CYC complex. These two loops may be able to operate independently but interact with each other through influence on the Gb’CLK/Gb’CYC. In addition, there are two other loops for rhythmic expression of Gb’Clk and Gb’cyc [12]