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. 2017 Apr 7;7:46164. doi: 10.1038/srep46164

Table 5. Adjusted prognostic values of the resulting signatures in present of other clinical factors.

  Forward: AC Forward: SCC Backward: AC Backward: SCC
β (p-value) β (p-value) β (p-value) β (p-value)
Signature (risk score) 1.6(9.2×10−7)* 1.85(0.02)* 3.01(3.4×10−6)* 4.24(0.02)*
Female versus male −0.27(0.39) −0.21(0.99) −0.23(0.46) −0.21(0.99)
Age 0.03(0.08) 0.04(0.37) 0.03(0.11) 0.02(0.69)
Smoking vs non-smoking 0.24(0.47) −2.18(0.05)* 0.26(0.43) −1.91(0.08)

Note: β: the estimated coefficient values in the multivariate Cox regression model using the prognostic signature, age, sex, and smoking status as covariates, representing the log hazard ratio. *p-value < 0.05, which is regarded as to be statistical significance.