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. 2017 Apr 7;7:45916. doi: 10.1038/srep45916

Table 3. Comparison of conjunctival hemodynamic descriptors in arterioles between C and DR subjects in unadjusted (Model 1) and adjusted (Model 2) models.

  D (μm)
V (mm/s)
Q (pl/s)
WSR (s−1)
WSS (dyne/cm2)
β P β P β P β P β P
Intercept 18 <0.001 0.69 <0.001 144 <0.001 278 <0.001 8.6 <0.001
Model 1: DR Stage Effect*
C Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref.
NDR 0.7 0.5 −0.16 <0.001 −21 0.3 −87 <0.001 −3.2 <0.001
NPDR 0.7 0.4 −0.07 0.2 −6 0.8 −47 0.04 −2.4 0.01
PDR 0.4 0.7 −0.04 0.4 8 0.7 −32 0.2 −1.8 0.05
Intercept 21 <0.001 0.98 <0.001 575 <0.001 755 <0.001 19.3 <0.001
Model 2: DR Stage Effect**
C Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref. Ref.
NDR 0.1 0.9 −0.11 0.01 −16 0.4 −60 <0.001 −2.2 <0.001
NPDR 0.8 0.4 0.02 0.7 14 0.5 −15 0.5 −1.1 0.2
PDR 0.9 0.4 0.00 0.1 13 0.6 −18 0.4 −0.9 0.3

C, NDR, NPDR, and PDR are abbreviations for non-diabetic control, no clinically visible diabetic retinopathy, non-proliferative diabetic retinopathy, and proliferative diabetic retinopathy, respectively. D, V, Q, WSR, and WSS are abbreviations for diameter, axial blood velocity, blood flow, wall shear rate and wall shear stress, respectively. Bold indicates statistical significance.

*Unadjusted.

**Adjusted for age, race, sex, mean arterial pressure, heart rate, hematocrit, and hemoglobin A1C.