. Author manuscript; available in PMC: 2018 Jan 1.

Published in final edited form as: J Diabetes Complications. 2016 Oct 5;31(1):67–73. doi: 10.1016/j.jdiacomp.2016.10.002

Table 3.

Repeated measures association of plasma PL (weight %) with TG, total C, LDL-C, HDL-C, and TG/HDL-C ratio in youth with T1D, unadjusted

	Plasma PL n-6 PUFA			Plasma PL n-3 PUFA			Estimated Desaturase Activity

	LA	DGLA	AA	ALA	EPA	DHA	D5D	D6D
	β (SE) for outcomes
Log-TG	0.001 (0.005)	0.01 (0.02)	−0.06 (0.01)^*	0.85 (0.18)^*	0.018 (0.026)	−0.06 (0.04)	−0.25 (0.05)^*	−0.01 (0.04)
Total C	0.11 (0.3)	−3.42 (1.21)^**	−1.63 (0.44)^**	34.97 (12.17)^**	5.2 (1.77)^**	−0.43 (2.61)	2.25 (3.09)	−7.82 (2.91)^**
HDL-C	0.33 (0.12)^**	−2.18 (0.5)^*	0.01 (0.18)	8.25 (5.02)	0.99 (0.73)	−1.13 (1.08)	4.64 (1.27)^**	−4.9 (1.19)^*
LDL-C	−0.29 (0.25)	−1.34 (1.01)	−0.66 (0.36)	10.84 (10.1)	3.94 (1.47)^**	2.09 (2.16)	1.36 (2.56)	−2.27 (2.41)
TG/HDL-C	−0.005 (0.006)	0.05 (0.02)^*	−0.06 (0.01)^*	0.68 (0.23)^**	−0.001 (0.033)	−0.05 (0.05)	−0.33 (0.06)^*	0.08 (0.05)

Abbreviations: LA = linoleic Acid (18:2n-6);DGLA = Di-homo-gamma-linoleic acid (20:3n-6); AA = Arachidonic Acid (20:4n-6); ALA - Alpha-linolenic Acid (18:3n-3); EPA = Eicosapentanoic Acid (20:5n-3); DHA = Docosahexaenoic acid (22:6n-3); D5D =Delta-5 desaturase calculated as AA/DGLA; D6D = Delta-6 desaturase calculated as DGLA/LA; HDL = high density lipoprotein; LDL = low density lipoprotein; C = cholesterol; TG = triglyceride; PL = phospholipid; T1D = type 1 diabetes; PUFA = polyunsaturated fatty acid; SE = standard error;

p<0.05;

^**

p<0.01