Figure 5. Summary of the order parameter measurements of the GHS receptor in the absence of ligand (filled bars) and in the presence of the agonist ghrelin (light filled bars) and the inverse agonist KbFwLK(Pam)-NH₂ (empty bars) performed this study.

Order parameters were determined from DipShift experiments conducted using CP excitation at a contact time of 700 μs (A,B) as well as by direct excitation (C,D). The GHS receptor was reconstituted into POPC (A,C) or DMPC membranes (B,D) and investigated at a temperature of 37 °C.