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. 2017 Apr 7;7:46290. doi: 10.1038/srep46290

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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BoxPlot (a) and frequency histogram (b) of the OncoScore distributions for non-cancer and cancer genes. (a) Each box plot is drawn between the lower and upper quartiles of the distributions with bold black line showing the median value. The OncoScore distributions of ‘Cancer’ and ‘Non-Cancer’ genes are significantly different (Mann-Whitney-Wilcoxon Test: p-value = 2.2e-16). (b) OncoScore frequency distribution plotted by equispaced breaks. (c) OncoScore and (d) Gene Ranker ranking plot of a mixed panel comprising ‘Cancer’ (*) and ‘Non-Cancer’ genes. The horizontal red lines identify the best cut-off classifier threshold models.

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