Table 1. Summary of the Clinical Features of Patients.
Clinical Characteristics | N |
---|---|
Age of Seizure Onset | |
<3 month | 24 |
3~6 month | 29 |
7~12 month | 15 |
Sex | |
Male:female | 47:21 |
Family History | |
Positive family history* | 9 |
Mother’s Pregnancy History | |
Spontaneous abortion | 3 |
Threatened abortion | 3 |
Pregnancy hypertension | 1 |
Premature labour | 2 |
EIEE Classification | |
West syndrome | 44 |
Dravet’s syndrome | 4 |
Ohtahara syndrome | 2 |
uEEEs | 18 |
Seizure Types | |
Spasms | 33 |
Spasms-tonic | 4 |
Tonic | 3 |
Tonic clonic | 12 |
Partial | 9 |
Multiple seizure types | 7 |
Head MRI or CT Scan | |
Normal | 39 |
Ventriculomegaly | 18 |
Arachnoid cyst | 3 |
Myelination delay | 1 |
Formation of CSP | 1 |
Cases where MRI or CT was not checked | 6 |
EEG | |
Hypsarrhythmia | 48 |
Sharp waves | 3 |
Slow waves | 2 |
Slow-spike-and-wave complexes | 2 |
Slow basic background activity | 1 |
Burst-suppresion | 4 |
Multiple epileptiform discharges | 8 |
Intellectual Disabilities (ID) | |
Mild | 18 |
Moderate | 20 |
Severe | 30 |
Response to AEDs Therapy | |
Seizures-free cases | 13 |
Seizures-controlled cases** | 16 |
AEDs resistant cases*** | 18 |
Deceased cases | 3 |
Cases we lost contact with | 8 |
*First-degree relative had history of epilepsy or intellectual disability.
**Seizures were considered controlled if the reduction of frequency of seizures attacks became more than 50% after treatment.
***Patients were considered resistant to treatment if the reduction of seizures attacks became less than 50% after taking AEDs.