Figure 6.

Primary sequences of α/β-peptide derivatives of 16 and 17, along with associated K_i values, as determined by VEGF₁₆₅ competition fluorescence polarization (FP) assay. Non-natural residues are indicated by colored circles, as depicted in Figure 4B. Each cysteine is engaged in an intramolecular disulfide bond. K_i values marked with a * are values previously reported for these compounds.^[26] See Figure S1 for derivation of K_i values and a discussion of experimental uncertainty in FP measurements.