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. 2017 Apr 7;7:45740. doi: 10.1038/srep45740

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Copyright © 2017, The Author(s)

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Through light microscopy images we can observe that HK2-WT cells in situation control (A), even in confluence, do not migrate to the adjacent region of the culture plate. However stimulated with potassium oxalate (Ox), calcium oxalate (CaOx) and TGF-β1, HK2-WT cells and HK2T + siRNA migrate to the adjacent region (B and E). However, HK2 cells receiving BMP-7 (HK2 + BMP-7) (C) and HK2 cells overexpressing BMP-7 (HK2T) (D) behaved similarly to the control (CTL) situation. N = 15 for each group.