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. 2017 Feb 10;6(3):e1273310. doi: 10.1080/2162402X.2016.1273310

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© 2017 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 5. — CD33⁺/IDO1⁺ expressing MDSCs are found in CTCL. (A) Double immunofluorescence staining of CD33 (red) and IDO1 (green) in typical LyP, MF, and SPTCL specimens. The top panel row shows a LyP tissue section with many strong double positive IDO1⁺/CD33⁺ cells (yellow) and some single positive IDO1⁺ or CD33⁺ cells. The second panel row shows an MF tissue section with cells either positive for IDO1⁺ or CD33⁺ as well as a few double positive IDO1+/CD33⁺ cells at lower right. The third panel row from top shows a SPTCL with double positive IDO1+/CD33⁺ cells as well as single positive cells (40x). In addition, IDO1 is expressed by both (B) CD30-positive and (C) CD30-negative cells in LyP (40x magnification). (Scale bar 20 µm).