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Prognostic impact of (A) combined HPV viral load/CD8+ expression and (B) combined HPV viral load/PD-1 expression and (C) combined HPV viral load/PD-L1 expression and (D) combined HPV viral load/FOXP3 expression on cumulative incidence of local recurrence and disease-free survival, as indicated. Analysis was based on the dichotomized total score in patient tumor samples (cut-off according to median value of total score).
