Table 2.
Different effects of leptin on appetite, energy metabolism, and glycemia as well as the response to fasting in various teleost species.
| Speciesa | Leptin source | Appetite | Energy metabolism | Glycemia | Fasting | Reference |
|---|---|---|---|---|---|---|
| Grass carp (Ctenopharyngodon idella) | Carp | Anorexigenic | ↑ lipolytic enzyme mRNA | ? | ? | Li et al. (21) |
| Catfish (Pelteobagrus fulvidraco) | Human | ? | ↑ lipolytic enzyme mRNA | ? | ? | Song et al. (39); Zhang et al. (70) |
| ↑ enzyme activity | ||||||
| ↓ triglycerides | ||||||
| Striped bass (Morone chrysops x Morone saxatilis) | Human | Anorexigenic | ? | ? | ↓ lep mRNA | Won et al. (10) |
| Tilapia (Oreochromis mossambicus) | Tilapia | ? | ↓ glycogen | Hyperglycemic | ↑ lepa mRNA | Baltzegar et al. (71); Douros et al. (42) |
| ↓ lipolytic enzyme mRNA | ↑ plasma leptin A | |||||
| Rainbow trout (Oncorhynchus mykiss) | Salmonid | Anorexigenic | ↓ glycogen | Hyperglycemic | ↑ plasma Lep | Murashita et al. (12); Kling et al. (72); Aguilar et al. (36, 37) |
| Goldfish (Carassius auratus) | Human | Anorexigenic | ↑ glycogen | Hypoglycemic | No effect? | de Pedro et al. (58); Vivas et al. (59); Tinoco et al. (28) |
| ↓ lipids |
The source of leptin indicates whether homologous or heterologous leptin was used in the study.
aSpecies were chosen to highlight the disparate effects of leptin observed in teleosts.