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. 2017 Mar 15;4(1):e000541. doi: 10.1136/openhrt-2016-000541

Table 4.

Cox regression analysis for all-cause mortality during long-term follow-up in the group of patients with STEMI who survived the first 30 days post-STEMI

Univariate Multivariate
HR 95% CI p Value HR 95% CI p Value
Gender (male) 0.99 0.56 to 1.73 0.96
Age (years) 1.07 1.04 to 1.09 <0.001 1.05 1.03 to 1.08 <0.001
Diabetes 2.28 1.27 to 4.12 0.006 1.82 0.99 to 3.34 0.054
Hypercholesterolaemia* 0.46 0.20 to 1.06 0.07
Hypertension 1.20 0.74 to 1.96 0.46
Current smoker 0.91 0.56 to 1.48 0.71
Family history of CAD 0.57 0.33 to 0.97 0.04 0.75 0.43 to 1.32 0.32
Presenting in Killip class≥2 1.47 0.53 to 4.05 0.46
Culprit vessel
 Left main 9.49 2.31 to 38.94 0.002 8.40 1.89 to 37.39 0.005
 RCA 0.86 0.52 to 1.40 0.54
 LAD 1.24 0.77 to 2.00 0.39
 LCx 0.71 0.34 to 1.48 0.35
Three-vessel CAD 1.95 1.21 to 3.16 0.006 1.34 0.80 to 2.23 0.26
eGFR ≤60 mL/min/1.73 m2 2.50 1.40 to 4.44 0.002 0.93 0.48 to 1.80 0.83
Peak cardiac troponin T level ≥3.5 µg/L 1.31 0.79 to 2.17 0.30
LV ejection fraction ≤40% 1.43 0.85 to 2.41 0.18
Medication at discharge
Beta-blocker 0.75 0.30 to 1.87 0.54
Aspirin 0.50 0.18 to 1.37 0.18
Clopidogrel 20.28 0.00 to 4,6·107 0.69
ACE inhibitor/ARB 0.76 0.24 to 2.42 0.64
Statin 0.81 0.11 to 5.86 0.84
Incomplete revascularisation 1.91 1.14 to 3.20 0.01 1.53 0.89 to 2.61 0.12

ARB, angiotensin receptor blockers; eGFR, glomerular filtration rate estimated using the Cockroft-Gault formula; LAD, left anterior descending coronary artery; LCx, left circumflex coronary artery; LV, left ventricle; PCI, percutaneous coronary intervention; RCA, right coronary artery; STEMI, ST-segment elevation myocardial infarction.

*

Serum total cholesterol ≥230 mg/dL and/or serum triglycerides ≥200 mg/dL or treatment with lipid-lowering drugs.

Defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or the use of antihypertensive medication.

Complete revascularisation was defined as treating all present significant coronary artery stenosis ≥70% during primary PCI or before discharge.