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. 2017 Jan 3;96(4):413–420. doi: 10.1177/0022034516683932

Figure 3.

Figure 3.

Condensed bone exhibits diminished osteogenesis coupled with elevated and prolonged resorption. Tartrate-resistant acid phosphatase (TRAP) activity on representative tissue sections from (A) a case where the implant was placed into drilled bone versus (B) a case where the implant was placed into condensed bone; dotted line indicates bone-implant interface. (C) Quantification of TRAP+ve pixels in the region of interest (ROI; see Appendix). Runx2 expression on a representative tissue section from (D) a case where the implant was placed into drilled bone versus (E) condensed bone; (F) quantification of Runx2+ve pixels in the ROI. Similar expression analyses of Osterix in (G) drilled versus (H) condensed bone; (I) quantification of Osterix+ve pixels. TRAP activity in (J) drilled versus (K) condensed bone on PID14; (L) quantification of TRAP+ve pixels in ROI. Similar analyses of alkaline phosphatase (ALP) activity in (M) drilled versus (N) condensed bone; (O) quantification of ALP+ve pixels. cb, cancellous bone; im, implant; PID, postinsertion day; po, periosteum. Scale bars = 100 µm. *P < 0.05.