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. 2016 Oct 4;242(3):275–285. doi: 10.1177/1535370216669839

Figure 5.

Figure 5

Administration of PI3K/Akt agonist 740 Y-P and inhibitor LY294002 affected the cell invasion and migration ability, viability, apoptosis in miR-205-5p HKF. (a) Representative images of transwell assays, administration of 740 Y-P and LY294002 affected migration and invasion ability in HKF. (b) Quantitative analysis results of CCK-8 assay, administration of 740 Y-P and LY294002 affected viability in HKF. (c) Expression level of p-AKT, fibrous protein, α-SMA in HKF treated with 740 Y-P and LY294002 compared to NC. Representative images of cell apoptosis as detected by flow cytometry, administration of 740 Y-P inhibited cell apoptosis in HKF. (d) Representative images of cell cycle distribution as detected by flow cytometry, administration of 740 Y-P had no impact on the cell cycle distribution in HKF. “*”, P < 0.05 compared with control group. (A color version of this figure is available in the online journal.)