Table 1.
Patient characteristics (summary)
| Biliary tract cancer (Klatskin tumor, gallbladder carcinoma, distal CCa) | Metastatic colorectal cancer | Total | |
|---|---|---|---|
| Number of patients | 84 | 4 | 88 |
| Gender (male:female) | 51:33 | 3:1 | 54:34 |
| Age (range) | 69 years (28–86) | 73 years (69–81) | 69 years (28–86) |
| Co-therapies | CHT = 20, S = 6, RFA = 1, EI = 1 | CHT = 4, S = 3, RFA = 1, RT = 1, SIRT = 1 | CHT = 24, S = 9, RFA = 2, RT = 1, EI = 1, SIRT = 1 |
| PDT sessions | 1 × = 58, 2 × = 11, 3 × = 5, 4 × = 5, 5 × = 3, 7 × = 2 | 1 × = 2, 2 × = 2 | 1 × = 60, 2 × = 13, 3 × = 5, 4 × = 5, 5 × = 3, 7 × = 2 |
| Adverse events within 30 days post-PDT | Cholangitis = 20, E. coli sepsis = 2, Klebsiella sepsis = 1, liver abscess = 1, non-ST-elevated myocardial infarction = 1, Clostridium difficile colitis = 1, acute renal failure = 1 | Cholangitis = 1, transfusion-dependent anemia = 1 | (as listed) |
| Survival after first PDT/initial diagnosis (95% CI) | 12.1 m/15.5 m | 16.3 m/128.1 m | 12.4 m (9.7–14.9 m) |
PDT: photodynamic therapy; CCa: cholangiocarcinoma; CHT: chemotherapy; CI: confidence interval; EI: ethanol injection; RFA: radiofrequency ablation; RT: radiotherapy (external), S: surgery; SIRT: selective internal radiotherapy; CI: confidence interval; m: months.