Table 2.
Gene | IS baseline* (n = 10) | IR baseline* (n = 10) | P baseline | IS ∆ | IR ∆ | P ∆ |
---|---|---|---|---|---|---|
Glut4 | 1.1 ± 0.52 | 0.62 ± 0.41 | 0.02 | −0.08 ± 0.33 | 0.47 ± 0.50‡ | 0.01 |
FABP4 | 1.08 ± 0.22 | 0.89 ± 0.28 | 0.08 | −0.21 ± 0.21‡ | 0.13 + 0.41 | 0.04 |
PEPCK | 1.00 ± 0.22 | 0.67 ± 0.24 | 0.003 | −0.18 ± 0.24† | 0.16 ± 0.37 | 0.01 |
ACC1 | 1.67 ± 1.1 | 1.13 ± 0.74 | 0.21 | 0.29 ± 0.99 | 0.49 ± 0.72 | 0.53 |
CD36 | 1.21 ± 0.40 | 1.08 ± 0.31 | 0.37 | −0.03 ± 0.46 | 0.08 ± 0.52 | 0.52 |
FATP1 | 1.00 ± 0.17 | 0.85 ± 0.22 | 0.06 | −0.14 ± 0.19† | 0.10 ± 0.36 | 0.08 |
LPL | 1.44 ± 0.55 | 1.22 ± 0.40 | 0.29 | 0.02 ± 0.61 | 0.23 ± 0.53 | 0.39 |
HSL | 1.35 ± 0.37 | 1.02 ± 0.35 | 0.049 | −0.19 ± 0.30 | 0.30 ± 0.56 | 0.03 |
ATGL | 1.47 ± 0.32 | 1.07 ± 0.29 | 0.01 | −0.30 ± 0.39† | 0.17 ± 0.26 | 0.006 |
*Baseline comparison adjusted for baseline %BF; change comparison adjusted for ∆%BF. Relative expression at peak weight was normalized to baseline expression for each gene and change calculated as the difference between peak weight and baseline relative expression;
†Paired t test comparing peak weight to baseline P < 0.05;
‡Paired t test comparing peak weight to baseline P < 0.01.