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Scanning electronic micrograph of the biologic scaffold in vitro. A: Plasma/thrombin mix. Fibrin polymerizes forming an intricate three-dimensional network (bar = 5 µm). B: Untreated human islet cell surface in culture medium (bar = 50 µm). C: Human islets embedded within the biologic scaffold. The polymerized fibrin forms an orthomorphic matrix around the islet surface (bar = 50 µm).
