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. Author manuscript; available in PMC: 2017 Apr 7.
Published in final edited form as: Arch Osteoporos. 2015 Oct 19;10:36. doi: 10.1007/s11657-015-0241-4

Table 3. Risk of osteoporotic fracture among Danish subjects taking allopurinol, using 1:1 matching.

Hip fracture Major fracture

Men Women All Men Women All

Model 1 1.13 (1.03, 1.24) 1.07 (0.99, 1.16) 1.10 (1.03, 1.16) 1.22 (1.16, 1.29) 1.04 (0.99, 1.09) 1.12 (1.08, 1.16)
Model 2 1.09 (0.99, 1.20) 1.03 (0.95, 1.12) 1.05 (0.99, 1.12) 1.20 (1.14, 1.27) 1.00 (0.95, 1.05) 1.08 (1.04, 1.13)
Model 3 1.11(1.01, 1.23) 1.05 (0.96, 1.14) 1.10 (1.00, 1.14) 1.21 (1.14, 1.29) 1.00 (0.95, 1.06) 1.09 (1.05, 1.14)

Figures given are HRs, with 95% CIs

Model 1: allopurinol use

Model 2: allopurinol use, prior fracture, known comorbidity

Model 3: allopurinol use, prior fracture, known comorbidity, drug history