Table 4. Risk of osteoporotic fracture among Danish subjects with a hospital diagnosis of gout, taking allopurinol, using 1:1 matching.
Hip fracture | Major fracture | |||||
---|---|---|---|---|---|---|
Men | Women | All | Men | Women | All | |
Model 1 | 1.36 (1.12, 1.66) | 1.14 (0.94, 1.39) | 1.25 (1.08, 1.44) | 1.41 (1.25, 1.58) | 1.13 (0.99, 1.29) | 1.28 (1.17, 1.39) |
Model 2 | 1.36 (1.1, 1.67) | 1.04 (0.85, 1.29) | 1.17 (1.01, 1.36) | 1.38 (1.22, 1.56) | 1.07 (0.93, 1.23) | 1.23 (1.13, 1.35) |
Model 3 | 1.44 (1.16, 1.79) | 1.04 (0.84, 1.30) | 1.21 (1.04, 1.41) | 1.43 (1.26, 1.62) | 1.08 (0.93, 1.25) | 1.26 (1.15, 1.39) |
Figures given are HRs, with 95% CIs
Model 1: allopurinol use
Model 2: allopurinol use, prior fracture, known comorbidity
Model3: allopurinol use, prior fracture, known comorbidity, drug history