Table 2. Top one enriched GO terms in the main ten modules.
| Module | Size | Degree | BP | CC | MF | |||
|---|---|---|---|---|---|---|---|---|
| GO term | p-value | GO term | p-value | GO term | p-value | |||
| M37 | 305 | 10 | Oxidative phosphorylation | < 1E-100 | Mitochondrial membrane part | <1 E-100 | Hydrogen ion transmembrane transporter activity | < 1E-100 |
| M65 | 184 | 16 | Ion transport | 2.29E-43 | Calcium channel complex | 9.34E-47 | Gated channel activity | 3.87E-53 |
| M80 | 52 | 15 | Regulation of TOR signaling cascade | 8.69E-13 | Cytosol | 1.31E-07 | Protein serine/threonine kinase activity | 4.76E-05 |
| M114 | 53 | 11 | Regulation of fatty acid oxidation | 4.68E-22 | AMP-activated protein kinase complex | 1.90E-11 | Protein serine/threonine kinase activity | 2.68E-15 |
| M145 | 7 | 3 | Negative regulation of cyclase activity | 8.16E-10 | Integral to plasma membrane | 2.81E-07 | Glutamate receptor activity | 8.27E-19 |
| M155 | 141 | 13 | Ion transport | 4.02E-69 | Ion channel complex | 6.63E-83 | Gated channel activity | 6.01E-98 |
| M188 | 43 | 6 | Synaptic transmission, cholinergic | 1.10E-28 | Nicotinic acetylcholine-gated receptor-channel complex | 5.90E-38 | Nicotinic acetylcholine-activated cation-selective channel activity | 9.95E-35 |
| M197 | 50 | 11 | Membrane invagination | 1.35E-09 | Coated pit | 5.83E-07 | Lipoprotein binding | 1.68E-09 |
| M208 | 34 | 6 | Muscle organ development | 3.62E-09 | Dystrophin-associated glycoprotein complex | 1.09E-42 | Calcium ion binding | 8.94E-04 |
| M230 | 45 | 8 | Protein localization | 6.44E-15 | Endosome | 3.62E-29 | ||
Size means the number of proteins in each module. Degree corresponds to number of edges connected with module. The function of a module is very similar to those of the proteins in it. The p-value is negatively related to the enrichment.