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Pharmacokinetic parameter ratios (GMR) of DDI.
Notes: Inhibition study with fluconazole (A); induction study with rifampin (B). Wilcoxon signed-rank test comparing GMR of pharmacokinetic parameters in microdose and regular-dose conditions.
Abbreviations: AUC, area under the (plasma concentration–time) curve; Cmax, maximum plasma concentration; GMR, geometric mean ratio.
